Uruguay forward Edinson Cavani scored twice to earn the South Americans a 2-1 win over European champions Portugal in their World Cup round of 16 clash on Saturday and set up a quarter-final against France.
Uruguay beat Portugal 2-1 in the last-16 to send Ronaldo and his team-mates packing, and the exit could signal the end of the superstar's worldwide career.
Ronaldo will be 35 by the next European Championship, and 37 by the next World Cup in Qatar.
For the first time in their history, the Uruguayan national football team took the nine points in a World Cup group stage.
Uruguay earned its date with the star-filled French by ousting Cristiano Ronaldo and Portugal 2-1 in the round of 16, the first true test of the tournament for Uruguay after La Celeste cruised through the group stage by dispatching Egypt, Saudi Arabia and Russian Federation without allowing a goal.
"I am sure that Portugal will continue to be one of the best teams in the world".
Cristiano Ronaldo lit up the World Cup in his own inimitable style, curling in a late free kick to complete a remarkable hat-trick in a group match between Portugal and Spain.
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"We must congratulate Uruguay because they are the national team that are in the quarter-finals", he said in his post-match interview. We're talking about great teams and players.
Not only does he praise Óscar Tabárez's side for reaching the quarter final stages, but he also congratulates Federation Internationale de Football Association and Russia for hosting the World Cup.
"We gave our best", Ronaldo said.
The pair combined for the opener, with Cavani's cross-field pass from the right flank finding Suarez.
Uruguay's team is built on being tough to break down and I fancy the likes of Godin and his defensive partners to starve the Portuguese of attacking opportunities. That run ended in the round of 16 at the World Cup, with Ronaldo again failing to score for his country in the knockout round of the tournament. But they stood firm after that and Cavani hit the victor with a curling strike into the far corner with his right foot. "Portugal had more possession and were often in our half of the pitch, and it would have been better for us to have more of the ball and play the game closer to their goal".
"I am not anxious defensively but we have to be careful, we have to be concentrated than other games". Among the youngsters expected to keep Portugal contending are midfielder Bernardo Silva and forwards Andre Silva, Goncalo Guedes and Gelson Martins, who are all 23 or younger. Those who control the midfield will dominate the match. "We prepared for this". "We have great players, a fantastic group".