There were no Israeli casualties.
Asked about those statements, an Israeli military spokeswoman said: "We do not respond to such foreign reports". The attack came as Israel fears reprisals for recent alleged attacks by it on Iranian targets in Syria.
There was no immediate comment from Israel, which nearly never confirms or denies airstrikes in Syria.
It should be noted that many Israelis who hold American citizenship received a message from the US Embassy in Israel not to travel to the Golan Heights. So, in early April, the media reported the possible involvement of the tel Aviv bombing base T-4 in HOMS.
SANA quoted a medical source saying that two civilians had died on a highway linking Damascus with the southern city of Deraa as a result of an explosion linked to "the Israeli aggression", without providing details.
An Israeli artillery unit takes position near the Syrian border in the Israeli-annexed Golan Heights, on May 9, 2018.
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Israel has warned it will not tolerate Tehran establishing itself militarily on its doorstep in Syria.
Israel has neither confirmed or denied responsibility.
His trip Wednesday came as Syrian state-run media said Israel struck a military outpost near the capital, Damascus, the previous night. According to the Britain-based Syrian Observatory for Human Rights, the Israeli missiles were fired at Iranian rocket launchers that were aimed toward Israel.
"They want to build a second Hezbollah-stan", he said, referring to the Iranian-backed Lebanese Shiite militant group that last fought a war with Israel in 2006.