In terms of passenger numbers, the flight between Hong Kong and the Taiwanese capital remains the busiest with 6.5 million passengers on the route.
In a top-20 list dominated by Asia, the highest-ranking route outside the region ran between NY and Toronto.
Kuala Lumpur-Singapore is now the busiest worldwide route in the world, knocking former leader Hong Kong-Taipei from the top spot according to the latest figures from industry analyst OAG. In contrast, there was only two within Europe and North America, respectively; and one in the Middle East.
The Singapore-Kuala Lumpur route is the busiest worldwide air link in the world despite the surprising fact that a flight between the two destinations lasts barely more than an hour. The combined OTP of all carriers serving the route from LGA to YYZ is 51 percent - a low average, likely resulting from a combination of the tough winter climates in NY and Toronto, and the combined congestion at the two airports.
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New York LaGuardia to Toronto, Canada crept in at eighth place, followed by Dubai to Kuwait in the rich Gulf States.
OAG's report found that the busiest global route outside of Asia was between New York's LaGuardia airport and Toronto Pearson - a route which saw about 16,956 flights over the period.
The world's busiest airline routes are heavily concentrated in Asia. In the other direction, NY is the final destination for 61 percent of passengers that travel from London, while 39 percent of travelers connect through JFK airport to other cities. Los Angeles is also the third top forwarding destination for those connecting through Shanghai (PVG) from Hong Kong (HKG).
A majority of the most highly trafficked air routes were in Asia, with 14 out of the top 20 being in the region. Singapore's Changi Airport was featured four times. Cancelations are also included.