Rex Tillerson is out as secretary of State, The Washington Post reported, ending a tumultuous tenure as America's top diplomat that was marked by a series of public disagreements with his boss - President Donald Trump.
Trump also had words of praise for Tillerson: "Finally, I want to thank Rex Tillerson for his service".
According to the Associated Press, Tillerson had returned from a shortened trip to Africa just hours before the announcement.
Tillerson navigated storms involving Trump's decision to cease implementing the Paris Climate Accord, escalating tensions with the North Korean regime, and questions over Russian meddling in the 2016 election.
British Police Investigating Suspicious Substance at Parliament
London Ambulance Service said it had attended the scene and taken a man and a woman to a nearby hospital as "precaution". Last month, police investigated white powder sent to an office in parliament, which was later found to be harmless.
Pompeo will replace him at the State Department, and Gina Haspel - the deputy director at the CIA - will succeed him at the CIA, becoming the first woman to run the spy agency, if confirmed.
Trump and Tillerson, the former CEO of Exxon Mobile, have reportedly been at odds for months. Trump offered no explanation for the change.
President Trump is pushing out Secretary of State Rex Tillerson and replacing him with Central Intelligence Agency director Mike Pompeo.
This is a developing story.