Three months later the 55-year-old was sacked following an income of just three points from nine games which left the Tigers in the relegation zone.
Some bosses often turn to players with whom they've worked before in such situations, so could Adkins do the same?
Slutsky and Hull parted company on Sunday evening, after the Russian made a hard start to life in the Sky Bet Championship, guiding the Tigers to just four victories from their opening 20 fixtures of the season.
Adkins, who is joined by assistant Andy Crosby, will oversee training on Friday morning and will be in the dugout for Saturday's championship clash at home to Brentford.
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Adkins, who left his last position at Sheffield United in May 2016, said: "I had a good conversation with the owner until late last night and obviously after the manager left, there was a decision to be made by the present owner". Having earned back-to-back promotions with Southampton when he took the Saints from League One to the Premier League, he has also won promotion when managing at Scunthorpe United in 2007 and 2009.
Hull have moved quickly to replace Slutsky, and for the club's supporters that is the most important thing.
Adkins has previous experience of winning promotion on his CV.
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