Brown, who was named the team's top executive by owners Dee and Jimmy Haslam during an overhaul following the 2015 season, was relieved of his duties on Thursday.
ESPN's Adam Schefter and Dianni Russini reported the news.
The Browns were a shockingly bad 1-27 with Brown running the personnel department, but the Boston native and Harvard Law School graduate was able to stockpile some serious assets during his brief tenure that will leave a nice present for his successor. The 2018 draft and off-season is pivotal for our franchise, we need to ensure that we maximize our opportunity for success; with our picks, free agency and building our roster.
Baker Mayfield named 2017 AP Player of the Year
He's averaging 8.3 yards per carry, has 17 touchdowns and set the FBS record with 12 runs of at least 50 yards this season. Last season, the Cardinals went 9-4 (7-1 in ACC play) while making it to the prestigious Citrus Bowl.
Haslam also announced Jackson will remain as coach for next season.
What comes next for the Cleveland Browns front office now that Sashi Brown is out?
After allowing right tackle Mitchell Scwartz, safety Tashaun Gipson and receiver Travis Benjamin to walk in free agency in 2016, Brown and the Browns made 24 draft selections and almost 20 trades to lay the foundation for the rebuilt roster since.
Brown's regime has been marked with strikeouts at the quarterback position, namely trading out of the No. 2 spot in the 2016 National Football League draft as Philadelphia moved up to select Carson Wentz. The team now holds 10 picks for 2018.