The 34-year-old is yet to feature for the Citizens this season and was not named as a substitute in Saturday's 5-0 victory over Liverpool.
Guardiola coached Toure at Barcelona, where the former Ivory Coast worldwide lost his place in the first XI and was transferred to City in 2010.
The Brazilian stopper was stretchered off during City's 5-0 win over Liverpool on Saturday, with Mane shown a red card after his high boot caught Emerson on the cheek.
Toure was left out of the squad by Guardiola and the manager raised fresh doubts over the veteran midfielder's future by refusing to make public why.
A final decision over his fitness will be made on Wednesday but Guardiola revealed that City were testing him with similar situations to see whether his confidence had been affected by the incident. Kompany, not for the first time in his City career, was injured while on global duty, much to the chagrin of Pep Guardiola.
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"I would understand that [nervous] feeling, but in today's training session there were two or three long balls and he was there".
City defender John Stones praised the keeper's bravery, saying: "Ederson has got on with it straight away". His face - everyone has seen the stitches and swelling.
"The step for the English teams - the club teams and national teams - is to win one, or be close and then say, "OK, wow, we are there".
"The only thing we can do is to try to make them pay a price and play a game with lots of energy".